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MEKK2 inhibitor 1s
CAS No. ——
MEKK2 inhibitor 1s( MEKK2-IN-1s )
Catalog No. M16998 CAS No. ——
MEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMEKK2 inhibitor 1s
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NoteResearch use only, not for human use.
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Brief DescriptionMEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies.
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DescriptionMEKK2 inhibitor 1s (MEKK2-IN-1s) is a potent MEKK2 (MAP3K2) inhibitor with IC50 of 16 nM, inhibits MEKK2 and MEKK3 with similar potencies; displays activity in cell-based assays in which it inhibited ERK5 pathway activation in cells and inhibited cell migration in a scratch assay.
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In Vitro——
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In Vivo——
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SynonymsMEKK2-IN-1s
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PathwayMAPK/ERK Signaling
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TargetMEK
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RecptorMEK
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight338.363
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Molecular FormulaC19H18N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(Z)-8-ethoxy-2-((4-hydroxy-2-methylphenyl)imino)-2H-chromene-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ahmad S, et al. Biochem Biophys Res Commun. 2018 Jan 29;496(1):205-211.
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